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%A Griffiths-Jones, Sam %A Bateman, Alex %A Marshall, Mhairi %A Khanna, Ajay %A Eddy, Sean R. %T Rfam: an RNA family database %0 Journal Article %D 2003 %8 January 1, 2003 %J Nucleic Acids Research %P 439-441 %R 10.1093/nar/gkg006 %V 31 %N 1 %U http://nar.oxfordjournals.org/content/31/1/439.abstract %X Rfam Is a collection of multiple sequence alignments And covariance models representing non-coding RNA families. Rfam Is available on the web in the UK at http://www.sanger.ac.uk/Software/Rfam/ And in the US at http://rfam.wustl.edu/. These websites allow the user to search a query sequence against a library of covariance models, And view multiple sequence alignments And family annotation. The database can also be downloaded in flatfile form And searched locally using the INFERNAL package (http://infernal.wustl.edu/). The first release of Rfam (1.0) contains 25 families, which annotate over 50 000 non-coding RNA genes in the taxonomic divisions of the EMBL nucleotide database.

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