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  1. General remarks

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This Is a December 2014 release of 2003-2014 COGs constructed by Eugene Koonin 's group at the National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH).

#----------------------------------------------------------- 0.1. Citation

Galperin MY, Makarova KS, Wolf YI, Koonin EV.

Expanded microbial genome coverage And improved protein family annotation in the COG database.

Nucleic Acids Res. 43, D261-D269, 2015 <http: //www.ncbi.nlm.nih.gov/pubmed/25428365>

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<COGsncbi.nlm.nih.gov>

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  1. Notes

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#----------------------------------------------------------- 1.1. 2003-2014 COGs

This release contains 2003 COGs assigned To a representative Set Of bacterial And archaeal genomes, available at February 2014. No New COGs were constructed.

#----------------------------------------------------------- 1.2. GIs And Refseq IDs

Sequences in COGs are identified by GenBank GI numbers. GI numbers generally are transient. There are two ways To make a more permanent link between the protein In COGs And the outside databases: via the RefSeq accession codes (see 2.5) And via the protein sequences (see 2.6).

Note, however, that at the moment (April 02, 2015) RefSeq database Is in a state of transition; some of the <refseq-acc> entries are Not accessible. This accession table will be updated as soon as RefSeq Is stable.